Mr Aris Konstantopoulos

 Professional experience

• More than 20 years of experience
• Consultant Ophthalmologist, Nuffield Wessex (present)
• Consultant Ophthalmologist, Spire (present)
• Fellow in Cornea, External Eye Disease and Refractive Surgery, Singapore National Eye Centre, (April 2014 - May 2015)
• Corneal Research Fellow, University of Southampton (February 2012 - March 2014)
• Corneal Clinical Fellow, University Hospital Southampton NHS Foundation Trust (February 2012 - March 2014)
• Ophthalmology Specialty Registrar, Wessex and Oxford Deaneries (December 2004 - March 2014)

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 Sub-specialties

• Cornea cataract and laser refractive surgery

 Education

• MBChB, University of Glasgow (1999)
• MRCOphth, The Royal College of Ophthalmologists, London (2005)
• MSc, Immunology and Immunogenetics, The University of Manchester (2009)
• FRCOphth, The Royal College of Ophthalmologists, London (2013)
• PhD, OCT Imaging and Quantification of Corneal Inflammation, University of Southampton (2017)

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 Publications and conferences

• Konstantopoulos A, Williams CPR, Newsom RS and Luff AJ. Ocular morbidity associated with intravitreal triamcinolone acetonide. Eye 2007; 21:317-320. [Clinical Study article]
• Konstantopoulos A, Williams CPR and Luff AJ. Outcome of intravitreal triamcinolone acetonide in post-operative cystoid macular oedema. Eye 2008; 22:219-222. [Clincal Study article]
• Konstantopoulos A and Luff AJ. Association of sleep apnoea and non-arteritic ischaemic optic neuropathy. Br J Ophthalmol, E-letter.
• Konstantopoulos A, Yadegarfar G and Elgohary M. Near work, education, family history and myopia in Greek conscripts. Eye 2008; 22:542-546. [Clinical Study article]
• Williams CPR, Konstantopoulos A, Rowley SX and Luff AJ. Late intraocular pressure rise after intravitreal triamcinolone. Clin Exp Ophthalmol 2007; 35:385-386. [Case Series article]
• Konstantopoulos A, Hossain PN and Anderson DF. Recent advances in anterior segment imaging devices: a new era in ophthalmic diagnosis? Br J Ophthalmol 2007; 91:551-557. [Perspective article]
• Konstantopoulos A, Madhusudhana K, Yadegarfar G and Lotery A. Age and complication rate in cataract surgery. Br J Ophthalmol 2007; 91:1254. [Letter]
• Konstantopoulos A, Kuo J, Anderson DF and Hossain PN. Assessment of the use of anterior segment optical coherence tomography in microbial keratitis. Am J Ophthalmol 2008; 146:534-542. [Clinical Study article]
• Konstantopoulos A, Yadegarfar G, Madhusudhana K, Canning CR, Luff AJ, Anderson DF, Hossain PN. Prognostic factors that determine visual outcome following cataract surgery complicated by vitreous loss. Eur J Ophthalmol 2009; 19:247-253. [Clinical Study article]
• Konstantopoulos A and Hossain PN. Limitations of Fourier Domain OCT. J Cataract and Refractive Surgery 2010; 36:534. [Letter]
• Konstantopoulos A, Yadegarfar G, Fievez M, Anderson D, Hossain P. In-vivo quantification of bacterial keratitis with optical coherence tomography. Invest Ophthalmol Vis Sci 2011; 52:1093–1097. [Clinical study article]
• Milia M, Konstantopoulos A, Stavrakas P, Toufeeq A. Pseudoexfoliation and opacification of intraocular lenses. Case Report Ophthalmol. 2011;2:287-90.[Case series article]
• Shinton AJ, Tsatsos M, Konstantopoulos A, Goverdhan S, Elsahn AF, Anderson DF, Hossain P. Impact of graft thickness on visual acuity after Descemet's stripping endothelial keratoplasty. Br J Ophthalmol 2011;96:246-9. [Clinical Study article]
• Konstantopoulos A, Yadegardar M, Yadegarfar G, Stinghe A, Macleod A, Jacob A, Hossain P. Deep sclerectomy versus trabeculectomy: a morphological study with anterior segment optical coherence tomography. Br J Ophthalmol 2013;97:708-14. [Clinical Study article]
• Tsatsos M, Konstantopoulos A, Hossain P, Anderson D. Presoaking with BSS used for thin manually dissected DSEK (TMDSEK): a viable option for thin DSEK. Eye. 2014;28:701-4.
• Konstantopoulos A, Mehta JS. Conventional Versus Accelerated Collagen Cross-Linking for Keratoconus. Eye Contact Lens. 2015;41:65-71.
• Konstantopoulos A, Mehta JS. Surgical compensation of presbyopia with corneal inlays. Expert Rev Med Devices. 2015;12:341-52.
• Liu YC, Konstantopoulos A, Riau AK, Bhayani R, Lwin NC, Teo EP, Yam HF, Mehta JS. Reproducibility of corneal biometric measurements using the Visante Omni and a rabbit experimental model of post-surgical corneal ectasia. Transl Vis Sci Technol. 2015;4:16.
• Hossain P, Konstantopoulos A. Blepharitis: remains a diagnostic enigma. A role for tea tree oil shampoo? Eye (Lond). 2015 Aug 21. doi: 10.1038/eye.2015.139. [Epub ahead of print]
• Konstantopoulos A, Tan XW, Goh GT, Saraswathi P, Chen L, Nyein CL, Zhou L, Beuerman R, Tan DT, Mehta J. Prophylactic Vancomycin Drops Reduce the Severity of Early Bacterial Keratitis in Keratoprosthesis. PLoS One. 2015 Oct 13;10(10):e0139653. doi: 10.1371/journal.pone.0139653.
• Tan XW, Thompson B, Konstantopoulos A, Goh TW, Setiawan M, Yam GH, Tan D, Khor KA, Mehta JS. Application of Graphene as Candidate Biomaterial for Synthetic Keratoprosthesis Skirt. Invest Ophthalmol Vis Sci. 2015;56:6605-11.
• Ang M, Konstantopoulos A, Goh G, Htoon HM, Seah X, Lwin NC, Liu X, Chen S, Liu L, Mehta JS. Evaluation of a Micro-Optical Coherence Tomography for the Corneal Endothelium in an Animal Model. Sci Rep. 2016;6:29769.
• Konstantopoulos A, Liu YC, Teo EP, Lwin NC, Yam GH, Mehta JS. Early wound healing and refractive response of different pocket configurations following presbyopic inlay implantation. PLoS One. 2017 Feb 24;12(2):e0172014.
• Turnbull AMJ, Tourkmani AK, Barbara R, Hossain PN, Anderson DF, Konstantopoulos A. Peripheral Corneal Hydrops Secondary to Pellucid Marginal Degeneration Managed With a Manually Dissected Semicircular Endothelial Keratoplasty Lenticule. Cornea. 2018 Aug;37(8):e41-e42. doi: 10.1097/ICO.0000000000001637.
• Konstantopoulos A, Liu YC, Teo EP, Nyein CL, Yam GH, Mehta JS.Corneal Stability of LASIK and SMILE When Combined With Collagen Cross-Linking. Transl Vis Sci Technol. 2019 May 20;8(3):21. doi: 10.1167/tvst.8.3.21.
• Tourkmani AK, Ansari AS, Hossain PN, Konstantopoulos A, Anderson DF. Tectonic Descemet Stripping Endothelial Keratoplasty for the Management of Corneal Perforation: A Case Series. Cornea. 2020 Dec;39(12):1571-1575. doi:10.1097/ICO.0000000000002424.
• Stellwagen A, MacGregor C, Kung R, Konstantopoulos A, Hossain P.Personal hygiene risk factors for contact lens-related microbial keratitis. BMJ Open Ophthalmol. 2020 Sep 8;5(1):e000476. doi: 10.1136/bmjophth-2020-000476. eCollection 2020.
• Tourkmani AK, Turnbull AMJ, Hossain PN, Konstantopoulos A, Anderson DF. Modified thin manual Descemet stripping endothelial keratoplasty with air-guided, non-pachymetric donor lenticule dissection: outcomes of graft thickness and complication rate. Int J Ophthalmol. 2020 Feb 18;13(2):342-345. doi: 10.18240/ijo.2020.02.19. eCollection 2020.
• Konstantopoulos A, Cendra MDM, Tsatsos M, Elabiary M, Christodoulides M, Hossain P. Morphological and cytokine profiles as key parameters to distinguish between Gram-negative and Gram-positive bacterial keratitis. Sci Rep. 2020 Nov 18;10(1):20092. doi: 10.1038/s41598-020-77088-w

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 Prizes and awards

• Southampton University Hospitals Innovation Competition Award, 2008 - runner up. Awarded for work on assessment of microbial keratitis with anterior segment OCT.
• Second congress of EuCornea, 2011: best paper in session. ‘Detection of different corneal inflammatory response in Gram negative and Gram positive bacterial keratitis'.
• Fourth congress of EuCornea, 2013: best paper in session. ‘Corneal tissue loss in bacterial keratitis is associated with the extent of inflammation at presentation’

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 Professional membership

• Membership of The Royal College of Ophthalmologists
• Member of European Society of Cataract and Refractive Surgeons
• Member of International Society of Refractive Surgery
• Member of Asia-Pacific Association of Cataract and Refractive Surgeons

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