Oesophageal cancer

What is oesophageal cancer?

Oesophageal cancer is a type of cancer that affects the oesophagus (gullet or food pipe), which is the long tube that carries food from the throat to the stomach. It occurs when abnormal cells grow in an uncontrollable way. It is more common in people in their 60s and 70s and occurs in men more than women.

What are the symptoms of oesophageal cancer?

The symptoms of oesophageal cancer include:

  • Difficulty in swallowing (dysphagia) – this feels like a pain or burning sensation in the throat or chest
  • Indigestion – occurs when acid from the stomach goes back into the oesophagus
  • Heartburn – which is a burning chest pain after eating
  • Weight loss – follows as a result of not being able to eat food because of the pain
  • Pain in the throat  - and behind the breastbone
  • A persistent cough
  • Dark poo – faeces may be almost black if the oesophagus bleeds from cancer

What are the causes of oesophageal cancer?

The exact cause is unknown but persistent gastro-oesophageal reflux disease (GORD), smoking, excessive alcohol consumption, being overweight and having an unhealthy diet are risk factors for the disease.

How is oesophageal cancer diagnosed?

The cancer is diagnosed using an endoscopy, which allows the doctor to see inside the oesophagus. The small, thin tube with a camera and light on the end is passed into the mouth and down towards the stomach. Sample tissues are removed so that they can be checked under a microscope.

What are the treatments for oesophageal cancer?

The treatment plan for oesophageal cancer depends on where in the oesophagus the cancer is and whether it is a squamous cell carcinoma or an adenocarcinoma. 

If it is diagnosed during an early stage, it may be possible to cure it with chemoradiotherapy or by treating with chemotherapy to first shrink it, followed by surgical removal of the affected area of the oesophagus. 

If the cancer is diagnosed at a later stage, cure is often not achievable but chemotherapy, sometimes in combination with targeted therapies such as immunotherapy, can be used to keep cancer under control and relieve symptoms

What’s the outlook for oesophageal cancer?

The outlook depends on the stage of oesophageal cancer. It depends on how far the disease has spread, the age, and the general health of the patient.

 10-25-2023
Top Doctors

Oesophageal cancer

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Professor Marco Gerlinger - Medical oncology

Created on: 04-28-2017

Updated on: 10-25-2023

Edited by: Conor Lynch

What is oesophageal cancer?

Oesophageal cancer is a type of cancer that affects the oesophagus (gullet or food pipe), which is the long tube that carries food from the throat to the stomach. It occurs when abnormal cells grow in an uncontrollable way. It is more common in people in their 60s and 70s and occurs in men more than women.

What are the symptoms of oesophageal cancer?

The symptoms of oesophageal cancer include:

  • Difficulty in swallowing (dysphagia) – this feels like a pain or burning sensation in the throat or chest
  • Indigestion – occurs when acid from the stomach goes back into the oesophagus
  • Heartburn – which is a burning chest pain after eating
  • Weight loss – follows as a result of not being able to eat food because of the pain
  • Pain in the throat  - and behind the breastbone
  • A persistent cough
  • Dark poo – faeces may be almost black if the oesophagus bleeds from cancer

What are the causes of oesophageal cancer?

The exact cause is unknown but persistent gastro-oesophageal reflux disease (GORD), smoking, excessive alcohol consumption, being overweight and having an unhealthy diet are risk factors for the disease.

How is oesophageal cancer diagnosed?

The cancer is diagnosed using an endoscopy, which allows the doctor to see inside the oesophagus. The small, thin tube with a camera and light on the end is passed into the mouth and down towards the stomach. Sample tissues are removed so that they can be checked under a microscope.

What are the treatments for oesophageal cancer?

The treatment plan for oesophageal cancer depends on where in the oesophagus the cancer is and whether it is a squamous cell carcinoma or an adenocarcinoma. 

If it is diagnosed during an early stage, it may be possible to cure it with chemoradiotherapy or by treating with chemotherapy to first shrink it, followed by surgical removal of the affected area of the oesophagus. 

If the cancer is diagnosed at a later stage, cure is often not achievable but chemotherapy, sometimes in combination with targeted therapies such as immunotherapy, can be used to keep cancer under control and relieve symptoms

What’s the outlook for oesophageal cancer?

The outlook depends on the stage of oesophageal cancer. It depends on how far the disease has spread, the age, and the general health of the patient.

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