Oestradiol HRT: How do the formulations differ?

In his latest online article, renowned women’s health expert and consultant gynaecologist Mr Mahantesh Karoshi dives into the world of hormone replacement therapy (HRT) and tells us about the different formulations of oestradiol and their effects on blood oestradiol levels.

What is the role of oestradiol?

Oestradiol is a hormone that is naturally produced by the ovaries in women. It plays a key role in regulating the menstrual cycle, bone health, and overall well-being. However, as women age and approach menopause, their levels of oestradiol decrease, which can lead to a range of symptoms such as hot flushes, mood swings, and vaginal dryness.

Is it used in hormone replacement therapy (HRT)?

HRT involves the use of hormones to replace those that are no longer produced in sufficient quantities by the body. Oestradiol is one of the most commonly used hormones in HRT, and it comes in a variety of different formulations, including pills, patches, creams, and injections.

How do the formulations differ?

Each formulation has its own benefits and drawbacks, and they can affect blood oestradiol levels in different ways. For example, oral oestradiol pills are absorbed by the liver, which can result in higher levels of oestradiol in the bloodstream. Transdermal patches, on the other hand, deliver a steady stream of oestradiol over a longer period of time, resulting in more stable blood levels.

It's important to note that the goal of HRT is not necessarily to achieve a specific blood oestradiol level, but rather to alleviate symptoms and improve overall quality of life. That being said, blood tests can be useful in a few situations to monitor hormone levels and adjust treatment as needed.

How do I know if HRT is the right choice for me?

If one is considering HRT, it's important to talk to your healthcare provider about the different options available and which one may be best for you based on your individual needs and medical history.

Remember, HRT is a personal decision and not everyone will choose to pursue it. But for those who do, it can be a valuable tool in managing symptoms and improving overall health and well-being.

If you would like to book a consultation with Mr Mahantesh Karoshi, you can do so today via his Top Doctors profile.