Women and epilepsy (Part 2): pregnancy, breastfeeding and safety

There are extra considerations for women with epilepsy while undergoing motherhood. However, this by no means implies that women with epilepsy cannot have a positive and normal experience during pregnancy, breastfeeding and life as a new mum. Professor Walker is a leading UK neurologist and researcher in the field of epilepsy who has worked with many women on the management of their condition, and in this article, he shares his knowledge and expertise.

Click here for part 1 - Women and epilepsy: hormones, periods and contraception

Can a seizure while pregnant affect the baby?

Experiencing an epileptic seizure during pregnancy poses only a small risk to the baby. On the other hand, convulsions (particularly repeat convulsions) or big seizures may cause a serious risk to the baby. For this reason, it’s highly important to have epilepsy under control during pregnancy.

After changing or coming off medication while pregnant, there is a severe risk of seizures which increases the risk to the mother and baby. To avoid seizures, it’s recommended that women take folic acid before becoming pregnant and that they discuss changes in medication with their neurologist before pregnancy.

Will epileptic drugs harm the baby?

A lot of drugs for epilepsy very slightly increase the risk of major foetal abnormalities, such as cleft lip and/or cleft palate and cardiac problems. With most drugs, this risk is only increased by a very small amount, from 1-3 out of 100 babies being affected.

However, growing evidence suggests that one drug, sodium-valproate, can have quite a marked effect during pregnancy with an increased risk of 6-7 per cent in conditions and malformations, depending on the dose. These are:

• Spina bifida
• Autism
• Learning difficulties

Furthermore, it’s already known that a baby’s exposure to sodium valproate will result in a lower IQ. Therefore, taking this drug during pregnancy is currently advised against, and should only be used in the lowest possible dose when there is no other sufficient drug.

Risks of epilepsy drugs in breastfeeding

Most epilepsy drugs are minimally excreted in breast milk. Therefore, for most drugs, there is no reason to advise against breastfeeding. Having said that, the mother must check that their drugs are in this safe group.

Safety regarding seizures around the baby

It’s beneficial for mothers to be extra wary of safety around the home once the baby is born. This is because there’s an increased risk of seizures due to stress and sleep deprivation. A few considerations are:

• For the mother not to bathe the child on her own in case she experiences a seizure while doing so.
• That the baby's pushchair has an automatic brake to stop itself if the mother lets go due to a seizure.
• To change the baby on the floor. If a seizure occurs, the baby won’t be left unattended on a high surface.
• To have the baby strapped to the mother rather than her holding it. If a seizure were to occur, the baby wouldn’t be unsupported and dropped.

Professor Matthew Walker is highly skilled in neurological disorders, including epilepsy. In 2013 he received the Ambassador for Epilepsy award from the International League Against Epilepsy. View his profile to learn more and to book a consultation.