What exactly is Mounjaro, and what does it do?

Written in association with:

Mr Sanjay Agrawal

Surgeon

Published: 03/10/2024
Edited by: Conor Lynch


Mounjaro (tirzepatide) is a new and innovative medication that has garnered attention for its potential to help people with weight loss, especially those who are struggling with obesity or related metabolic conditions. Originally developed for the treatment of type 2 diabetes, Mounjaro has shown significant weight loss benefits in clinical trials, making it a groundbreaking option for patients looking to manage their weight.

 

Manufactured by Eli Lilly, Mounjaro belongs to a class of drugs known as GLP-1 receptor agonists and GIP receptor agonists, which help regulate blood sugar levels and impact appetite.

How does it work?

Mounjaro works by mimicking two hormones naturally produced in the gut—GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These hormones play a key role in controlling blood sugar, but they also have a significant effect on appetite and metabolism.

 

Mounjaro primarily works by regulating your appetite, giving you a sense of satiety (‘fullness’), making you feel less hungry and experience less food cravings. This will help you eat less food and reduce your body weight

 

What clinical trials have shown about Mounjaro

Clinical trials for Mounjaro have shown remarkable results for weight loss. In a study of patients with type 2 diabetes, participants lost an average of 15% to 20% of their body weight over the course of the trial, depending on the dosage.

 

This has made Mounjaro one of the most effective medications for weight loss currently available. For individuals who are obese but do not have diabetes, similar studies are underway to assess its long-term efficacy and safety.

 

While Mounjaro presents a promising option for weight loss, it is not a magic pill. It is designed to be used alongside a healthy diet and regular exercise to maximize its benefits. The drug is generally well-tolerated, but like all medications, it comes with potential side effects.

 

The most common side effects reported are gastrointestinal issues such as nausea, diarrhoea, and vomiting, which tend to lessen over time as the body adjusts to the medication.

 

Mounjaro is available by prescription and should be used under the supervision of a healthcare provider. It is particularly beneficial for people who have struggled to lose weight through diet and exercise alone, or who have obesity-related health conditions such as diabetes or hypertension.

 

As more research emerges, Mounjaro could become a leading option in the fight against obesity, offering hope to millions of people looking for effective, long-term weight management solutions. 

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