Alkaline phosphatase analysis
Alkaline phosphatase is an enzyme present in various tissues of the body, such as the liver, bones, intestines, and kidneys. Its analysis is essential for evaluating bone and liver health, as well as for detecting certain medical conditions. Here is a detailed guide on this important analysis:
What is being analysed?
Alkaline phosphatase is an enzyme that is analysed in blood samples to assess liver and bone function.
How is it used?
The analysis of alkaline phosphatase is used to diagnose liver disorders, bone disorders, and gallbladder disorders. It is also used to monitor the progression of certain diseases and to assess the effectiveness of treatment.
Why perform the analysis?
The analysis of alkaline phosphatase is crucial for detecting and monitoring liver diseases, bone disorders such as osteoporosis, and gallbladder disorders. It can also help identify diseases related to phosphocalcic metabolism.
When to perform the analysis?
The analysis of alkaline phosphatase can be performed as part of a routine check-up, to diagnose specific symptoms, or to monitor the progression of a disease.
What sample is required?
A blood sample is required to perform the alkaline phosphatase analysis.
Is any prior preparation necessary?
No special preparation is required for this analysis. However, it is important to inform the doctor about any medications you are taking, as certain medications can affect alkaline phosphatase levels in the blood.
What are the normal values?
Normal alkaline phosphatase values can vary depending on age, sex, and other factors. Typically, normal levels range from 20 to 140 units per litre (U/L) in adults.
What does it mean to have altered values?
Elevated levels of alkaline phosphatase may indicate liver disorders such as hepatitis, biliary obstruction, cirrhosis, or liver cancer. They may also be related to bone disorders such as Paget's disease, bone fractures, bone tumours, or bone metastases.
On the other hand, low levels of alkaline phosphatase are less common but may be associated with nutritional deficiencies, hypothyroidism, anaemia, or genetic disorders.
Normal Alkaline Phosphatase Values (U/L)
Age Normal Range (U/L) Adults 20 - 140 Children (1-17) 70 - 400 Newborns 150 - 350Remember that reference values may vary slightly between different laboratories. If your results show values outside the normal range, it is important to consult your doctor for an accurate diagnosis and appropriate treatment plan.