Aspartate Aminotransferase (AST)

What is being analysed?

Aspartate Aminotransferase (AST) is an enzyme found in various tissues, especially in the liver, heart, and muscles. It plays a crucial role in the conversion of aspartate and alpha-ketoglutarate to oxaloacetate and glutamate. AST is analysed to assess the health of these tissues and organs.

What does the result mean?

Interpreting the results of AST analysis is essential. Elevated AST levels may indicate liver damage, heart issues, or muscle damage. Conversely, normal levels are generally associated with healthy tissue function.

 

Why perform the analysis?

AST analysis is performed to diagnose and monitor conditions affecting the liver, heart, or muscles. It helps in identifying diseases such as hepatitis, cirrhosis, or myocardial infarction. Timely analysis can aid in early intervention and treatment.  

 

When to conduct the analysis?

AST analysis is recommended in various scenarios, including routine check-ups, assessment of liver function, suspicion of cardiac issues, or monitoring certain medical treatments. The timing may vary based on the specific medical context.

 

Required sample for analysis?

A blood sample is required for AST analysis. A healthcare professional will draw blood, usually from a vein in the arm, and send it to the laboratory for testing.

 

Any necessary preparation?

Generally, no specific preparation is needed before AST testing. However, it's essential to inform the healthcare provider about any medications or supplements being taken, as certain drugs can affect AST levels.

 

How is it used?

AST analysis is used in a medical context to assist in the diagnosis and monitoring of liver, heart, and muscle conditions. It provides valuable information to healthcare professionals for treatment planning and patient care.

 

Normal values:

Age Group

Normal AST Levels (IU/L)

Adults

10 to 40

Children

10 to 60

 

Interpreting abnormal values:

Abnormal AST values may indicate underlying health issues: Elevated levels: Liver disease, heart problems, muscle injury. Decreased levels: Rare, but may be associated with severe liver damage.