Cerebrospinal Fluid Analysis

What is analysed?

Cerebrospinal fluid (CSF) analysis involves the examination of the clear, colourless fluid that surrounds the brain and spinal cord. This fluid plays a crucial role in protecting and nourishing the central nervous system.

What does the result mean?

The results of CSF analysis provide valuable insights into various neurological conditions. It helps in diagnosing infections, inflammatory disorders, bleeding, and certain tumours affecting the central nervous system.

 

Why undergo the analysis?

CSF analysis is conducted to identify and diagnose a range of neurological disorders. It aids healthcare professionals in determining the appropriate treatment plan based on the specific condition detected.

 

When to perform the analysis?

CSF analysis is typically recommended when there are symptoms or indications of neurological disorders such as meningitis, encephalitis, multiple sclerosis, or unexplained headaches. The timing is crucial for accurate diagnosis and timely intervention.

 

What sample is required?

A sample of cerebrospinal fluid is collected through a lumbar puncture or spinal tap. This procedure involves inserting a thin needle into the spinal canal to withdraw a small amount of fluid for analysis.

 

Is any prior preparation necessary?

Generally, there is no specific preparation required for CSF analysis. However, it is essential to inform your healthcare provider about any medications or allergies beforehand. They will provide specific instructions based on individual health conditions.

 

How is it conducted?

The collection of cerebrospinal fluid is performed by a trained healthcare professional. The patient is positioned carefully, and the procedure is carried out under sterile conditions to minimise the risk of infection.

 

What are the normal values?

The normal values for cerebrospinal fluid components, including protein, glucose, and cell count, vary.

Component

Normal Range

Protein

0.15 to 0.45 g/L

Glucose

2.5 to 4.5 mmol/L

Cell Count (WBC)

0 to 5 cells/mm³

Cell Count (RBC)

0 to 2 cells/mm³

What does it indicate to have altered values?

Abnormal CSF analysis results may indicate various conditions, such as infections, autoimmune disorders, bleeding, or tumours. Further diagnostic tests may be required to confirm the underlying cause and develop an appropriate treatment plan.