Cystatin C testing

What is analysed?

Cystatin C analysis involves measuring the concentration of cystatin C in the blood to assess kidney function.

What does the result mean?

The result indicates the level of cystatin C in the bloodstream, which reflects the glomerular filtration rate (GFR) and provides an estimate of kidney function.

Why undergo the analysis?

Cystatin C analysis is performed to evaluate kidney function, particularly in patients with suspected or known kidney disease, or to monitor renal function over time.

When to undergo the analysis?

Cystatin C analysis may be recommended as part of routine kidney function assessment or when there are concerns about kidney health.

What sample is required?

A blood sample is required for cystatin C analysis.

Is any prior preparation necessary?

No specific preparation is usually necessary before cystatin C analysis. Patients should follow any instructions provided by their healthcare provider.

How is it used?

Cystatin C levels are used to estimate GFR and assess kidney function independently of factors that may affect serum creatinine levels.

What are the normal values?

Normal cystatin C levels typically range between 0.53 and 0.95 mg/L. However, reference ranges may vary depending on the laboratory method used.

Cystatin C levels reference table

Cystatin C Level (mg/L) Interpretation Less than 0.95 Generally considered within normal range 0.95 or higher  May indicate impaired kidney function

This table provides a simplified interpretation of cystatin C levels, aiding healthcare professionals in assessing kidney function and diagnosing kidney-related conditions.

What do altered values signify?

Elevated cystatin C levels may indicate impaired kidney function or decreased GFR, suggesting underlying kidney disease or dysfunction.