Lactate dehydrogenase

What is being analysed?

Lactate dehydrogenase (LDH) is an enzyme found in almost all body tissues, with higher concentrations in the heart, liver, kidneys, skeletal muscle, brain, blood cells, and lungs. This analysis measures the level of LDH present in the blood.

What does the result mean?

The result indicates the amount of LDH in the blood. Elevated levels may indicate tissue damage or disease. However, LDH is not specific to any particular organ, so further investigation is needed to determine the underlying cause.

Why do the analysis?

LDH analysis is performed to assess tissue damage, monitor treatment response, and diagnose various medical conditions such as myocardial infarction (heart attack), liver disease, anaemia, and certain cancers.

When to do the analysis?

LDH analysis may be ordered as part of routine blood work, when symptoms suggest tissue damage or disease, or to monitor ongoing conditions and treatment effectiveness.

What sample is required?

A blood sample is required for LDH analysis, typically obtained through venipuncture from a vein in the arm.

Is any type of prior preparation necessary?

No specific preparation is needed for LDH analysis. However, it's important to follow any instructions given by your healthcare provider, such as fasting requirements.

How is it used?

LDH analysis is used in conjunction with other tests and clinical findings to diagnose and monitor various medical conditions. It helps healthcare providers assess tissue damage and disease progression.

What are the normal values?

The normal range for LDH levels in the blood can vary slightly depending on the laboratory and testing method used. However, typical reference ranges fall between 140 to 280 units per litre (U/L).

What does it mean to have altered values?

Elevated LDH levels may indicate tissue damage or disease, such as myocardial infarction (heart attack), liver disease, anaemia, infections, or certain cancers. However, LDH is not specific to any particular condition, so further testing is often needed to determine the underlying cause of elevated levels.

Table of LDH Values:

Age Group

Normal Range (U/L)

Adults

140-280

Children

Varies

Elderly

May be slightly higher

 

This table provides a general reference range for LDH levels in different age groups. However, individual laboratory reference ranges may vary, so it's essential to interpret results in consultation with a healthcare provider.