Mr Sinan Barazi

Pituitary, skull base, facial pain and spinal neurosurgeon in London

FRCS MRCSEd BSc MBBS

GMC: 4326395

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Professional statement

Mr Sinan Barazi is a leading London-based pituitary, skull base, trigeminal neuralgia/facial pain and spinal neurosurgeon. He was born in Copenhagen and subsequently moved to the United Kingdom where he attended Winchester College.

He qualified from King’s College Hospital School of Medicine in 1996, after which he completed his French military service in the 14th Parachute Regiment in Toulouse. He completed his surgical training in London at the Atkinson Morley Hospital, King’s College Hospital, and St George’s Hospital.

After finishing his specialist training, he worked in Bologna, Italy, as a fellow in endoscopic pituitary surgery under Giorgio Frank and Ernesto Pasquini, and finally in Manchester as a skull base fellow under Professor Andrew King and Scott Rutherford. He was appointed consultant skull base neurosurgeon at King’s College Hospital NHS Foundation Trust in 2011.

He is a core member of the Skull Base, Pituitary and Complex Facial Pain multi-disciplinary teams and he has established the Complex Facial Pain service with Dr Giorgio Lambru across the King’s College Hospital and St Thomas’ Hospital sites. He has published extensively in major neurosurgical journals and has presented at national and international meetings on a range of topics including pituitary, skull base and facial pain surgery.

Mr Barazi is a member of several professional organisations including the British Skull Base Society (BSBS) (where he has just completed three years as a council member), the Society of British Neurological Surgeons (SBNS) and the Royal College of Surgeons. He is the lead for the Royal College of Surgeons accredited Senior Fellowship in Skull Base, Pituitary and Facial Pain service at King’s College Hospital.

He was appointed joint chair of the Medical Advisory Board of the Trigeminal Neuralgia Association of the United Kingdon in 2023 alongside Dr Giorgio Lambru. His private practice is at the Harley Street Clinic, Cromwell Hospital, Chiswick Medical Centre, and the Guthrie Clinic at King's College Hospital. He is fluent in English, French, Danish, German and Swedish.

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Credentials

GMC: ‍4326395

Professional experience

• More than 25 years of experience
• Consultant neurosurgeon, Harley Street Clinic (2013 - present)
• Consultant neurosurgeon, London Neurosurgery Partnership (April 2013 - present)
• Consultant neurosurgeon, Cromwell Hospital (2011 - present)
• Consultant neurosurgeon, 78 Harley Street (Present)
• Consultant neurosurgeon, Chiswick Medical Centre (Present)
• Consultant neurosurgeon, King's College Hospital (2011 - present)

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Sub-specialties

• Pituitary disorders
• Skull base surgery
• Endoscopic skull and pituitary surgery
• Neck surgery
• Back surgery
• Odontoidectomy
• Basilar invagination
• trigeminal neuralgia
• facial pain
• vestibular schwannoma

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Positions in public associations

• Chair, Trigeminal Neuralgia Association (Present)
• Council member, British Skull Base Society (2019-2023)

Teaching posts

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Education

• FRCS (Neurol.Surgery)
• MBBS, Medicine, King's College Hospital School of Medicine, London (1990 - 1996)
• BSc

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Publications and conferences

• Fat in the Fossa and the Sphenoid Sinus: A Simple and Effective Solution to CSF Leaks in Transsphenoidal Surgery. Cohort Study and Systematic Review. Mirza AB et al. J Neurol Surg B Skull Base 2023; 84(02): 143-156
• Fully Endoscopic Microvascular Decompression for Trigeminal Neuralgia: Technical Note Describing a Single-Center Experience. HL Pak, G Lambru, M Okasha, E Maratos, N Thomas, J Shapey, S Barazi. World Neurosurgery Volume 166, October 2022;159-167
• AB Mirza, Akhbari M, Murphy C, Connor S, Howard MR, Reisz Z, Barazi S, Thomas N, Bodi I, Maratos E. Brain and Spine 2022. Spontaneous rupture of malignant papillary craniopharyngioma with CSF seeding and metastatic deposits: A case report and literature review. Available online 3rd August 2022.
• Low post-operative cortisol after TSS for pituitary surgery predicts short term but not long term remission. Vanitha Karunakaran , Mohamed Okasha , Nick W Thomas , Sinan Barazi , Eleni Maratos, Benjamin C Whitelaw , Jackie Gilbert , Paul V Carroll, Jonathan Shapey , and Simon J B Aylwin. Endocrine Abstracts (2022) 81 P175 | DOI: 10.1530/endoabs.81.P175
• Do All Notochordal Lesions Require Proton Beam Radiotherapy? A Proposed Reclassification of Ecchordosis Physaliphora as Benign Notochord Cell Tumor. Sooltangos A et al. J Neurol Surg B Skull Base 2022; 83(S 02): e96-e104
• Evidence-based surveillance protocol for vestibular schwannomas: a long-term analysis of tumor growth using conditional probability. Borsetto D et al. Journal of Neurosurgery Volume 137 Issue 4: 1026-1033;(February 2022)
• Endoscopic Endonasal Approach to Rare Clival Paraganglioma: Case Report and Review of Literature. Okasha M et al. SN Comprehensive Clinical Medicine 3, pages 2688–2693 (2021)
• CSF Rhinorrhea After Endonasal Intervention to the Skull Base (CRANIAL) — Part 2: Impact of COVID-19. Bandyopadyay S et al. World Neurosurgery Volume 149 May 2021, Pages e1090-e1097
• Neurosurgery and coronavirus: impact and challenges—lessons learnt from the first wave of a global pandemic. Keyoumars Ashkan et al. Acta Neurochirurgica volume 163, pages317–329 (2021)
• CSF Rhinorrhoea After Endonasal Intervention to the Skull Base (CRANIAL) - Part 1: Multicenter Pilot Study. Khan DZ et al. World Neurosurgery Volume 149, May 2021, Pages e1077-e1089
• Risk Factor Analysis and Surgical Outcomes of Acute Spontaneous Spinal Subdural Hematoma. An Institutional Experience of Four Cases and Literature Review. Vastani et al. World Neurosurgery Volume 146, February 2021, Pages e384-e397
• A snapshot of European neurosurgery December 2019 vs. March 2020: just before and during the Covid-19 pandemic. Mathiesen et al. Acta Neurochirurgica 162, 2221–2233 (2020)
• Refractory cyclical Cushing’s – clinical challenges. Banu Z et al. Endocrine Abstracts (2020) 69 P68
• Combined Supra- and Infra-Tentorial Retro-Labyrinthine Pre-sigmoid Approach. Thomas N, Maratos E, Barazi S. Current Otorhinolaryngology Reports. Volume 7. 195–199 (2019)
• Adult Parasellar Capillary Hemangioma with Intrasellar Extension. Low J, Maratos E, Kumar A, King A, al-Sarraj S, Barazi S. World Neurosurgery Volume 124, April 2019, Pages 184-191
• A single centre’s experience of managing spheno-orbital meningiomas: lessons for recurrent tumour surgery. Shapey J, Jung J, Barkas K, Barazi S, Bentley R, Huppa C, Thomas NW. Acta Neurochirurgica 161, 1657-1667 (2019)
• A standardised pathway for the surveillance of stable vestibular schwannoma. Shapey J et al. The Annals of The Royal College of Surgeons of England Volume 100 No. 3 (2017) (online 2018)
• Tumors of the Skull Base. Chapter in Surgery of the Skull Base. Practical Diagnosis and Therapy. Schick U et al. Springer Verlag (2017)
• Optic Nerve Decompression with Release of the Meningo-Orbital Band in Medial Sphenoid Wing Meningiomas Improves and Preserves Visual Acuity. Cheserem JB et al. J Neurol Surg B Skull Base 2016; 77 - FP-01-02
• Endonasal Endoscopic Transsphenoidal Surgery for Pituitary Macroadenomas: A Retrospective Analysis of Surgical Outcome. Paidakakos NA et al. J Neurol Surg B Skull Base 2014; 75 - a150
• Endocrine remission of Cushing's disease after endoscopic trans-sphenoidal surgery: Retrospective review of a single centre experience. Kennard D et al. Endocrine Abstracts (2013) 31 P257
• Pituitary metasases: patients presenting with cranial nerve palsies and diabetes insipidus: a single centre experience. Salaris P et al. Endocrine Abstracts (2013) 31 P158
• Paidakakos NA, Evans SA, Evans G, Barazi S, Thomas N. Endonasal Endoscopic Transsphenoidal Surgery for Pituitary Macroadenomas: A Retrospective Analysis of Surgical Outcome. J Neurol Surg B 2014; 75 - a150
• Barazi SA, d’Urso PI, Pasquini E, Zoli M, Mazzatenta D, Sciarretta V, Frank G. Extended endoscopic transplanum-transtuberculum approach for pituitary adenoma. Br J Neurosurg. 2013 Jun;27(3):374-82. Epub 2012 Nov 26
• Kennard D, Whitelaw B, Dworakowska D et al. Endocrine remission of Cushing's disease after endoscopic trans-sphenoidal surgery: Retrospective review of a single centre experience. Endocrine Abstracts (2013) 31 P257
• Salaris P, Kordbacheh T, Whitelaw B et al. Pituitary metasases: patients presenting with cranial nerve palsies and diabetes insipidus: a single centre experience. Endocrine Abstracts (2013) 31 P158
• Whitelaw BC, Dworakowska D, Thomas NW, Barazi S, Riordan-Eva P, King AP, Hampton T, Landau DB, Lipscomb D, Buchanan CR, Gilbert JA, Aylwin SJ. Temozolomide in the management of dopamine agonist-resistant prolactinomas. Clin Endocrinol (Oxf). 2012 Jun;76(6):877-86
• Grant P, Whitelaw B, Barazi S, Aylwin S. Salt and water imbalance following pituitary surgery. Eur J Endocrinol. 2012 Jul 30 – PAPER WITHDRAWN
• Shapey J, Barazi SA, Bodi I, Thomas NWM. Myxopapillary ependymoma of the cerebellopontine angle: retrograde metastasis or primary tumour? Br J Neurosurg. 2011 Feb;25(1):122-3. Epub 2010 Aug 13
• Barazi SA, Bodi I, Thomas NW. Sarcoidosis presenting as an isolated extradural thoraco-lumbar lesion mimicking tumour. Br J Neurosurg. 2008 Oct;22(5):690-1
• Barazi SA, Choo M, Martin AJ. CSF rhinorrhoea due to a pulsion diverticulum of the frontal horn. Br J Neurosurg. 2008 Aug;22(4):580-1
• Barazi S, Cudlip S, Marsh M. Awake craniotomy using Stealth frameless stereotaxy. Br J Neurosurg. 2006 Feb; 20(1):38-40
• Gnanalingham KK, Apostolopoulos V, Barazi S, O'Neill K. The impact of the international subarachnoid aneurysm trial (ISAT) on the management of aneurysmal subarachnoid haemorrhage in a neurosurgical unit in the UK. Clin Neurol Neurosurg. 2006 Feb;108(2):117-23. Epub 2005 Dec 20.
• Barazi SA, Selway RP, Tawari G, Polkey. CE. Outcome of Vagus Nerve Stimulation in 59 Patients with Intractable Epilepsy more than Six Years after implantation. Epilepsia Vol. 46, Suppl.6,2005
• Gnanalingham KK, Tysome J, Martinez-Canca J, Barazi SA. Quality of clinical studies in neurosurgical journals: signs of improvement over three decades. J Neurosurg. 2005 Sep;103(3):439-43.
• Barazi SA, Selway RP, Tawari G, Polkey CE. Does Vagus Nerve Stimulation (VNS Therapy) effectively treat intractable epilepsy and does it meet patients’ expectations? Epilepsia 2005; Vol. 46 (Suppl. 8):336 – P3.176
• Barazi S, Gnanalingham K, Chopra I, Van Dellen JR. Delayed postoperative intracerebral abscess caused by Proprionibacterium acnes: case report and review of the literature. Br J Neurosurg. 2003 Aug;17(4):336-9.
• Barazi S, Cudlip S, Johnston F. High and low pressure states associated with posterior sacral meningocele. Br J Neurosurg. 2003 Apr;17(2):184-7

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Prizes and awards

• King's College Hospital Commendation, King's College Hospital NHS Foundation Trust (2013)
• Medaille de la Defense Nationale 11eme Division Parachutiste (1998)
• Brevet Militaire de Parachutiste 11eme Division Parachutiste (1998)
• Best Oral Presentation British Neuroendoscopy Society (2022)

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Professional membership

• British Skull Base Society (BSBS)
• Society of British Neurological Surgeons (SBNS)
• Royal College of Surgeons, MRCS (Ed)

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Languages spoken

Danish
French
German
Swedish