All about platelet rich plasma (PRP) injections

Written in association with: Mr Saket Tibrewal
Published: | Updated: 31/07/2024
Edited by: Karolyn Judge

Considering platelet-rich plasma (PRP) injections but unsure where to start? Leading orthopaedic knee surgeon Mr Saket Tibrewal discusses this treatment in this article, considering the benefits, risks and procedure.

Blood sample to be used for PRP injection

What is platelet rich plasma (PRP)?

Our blood is made up of a liquid component called plasma. It also contains three main solid components:

  • the red blood cells (RBCs);
  • white blood cells (WBCs), and;
  • platelets.

Platelets play an important role in forming blood clots and also consist of special proteins known as growth factors, which help with our body’s healing process.

 

PRP is a high concentration of platelets and plasma. A normal blood specimen contains only six per cent of platelets, while platelet-rich plasma contains 94 per cent of platelets and 5 to 10 times the concentration of growth factors found in normal blood. This means it has greater healing properties.

 

 

What are the indications for PRP injections?

PRP is relatively new as a method of treatment for various orthopaedic conditions. These include:

 

The injections can help to relieve painful symptoms, promote healing and delay joint replacement surgery.

 

 

What’s involved in the platelet rich plasma injection procedure? 

First, your doctor will draw about 10 ccs of blood. This comes from the large vein in your elbow. This blood is then spun in a centrifuge machine for about 10 to 15 minutes to separate the platelets from the remaining blood components.

 

The injured part of your body is then anaesthetised with a local anaesthetic. Then, the platelet-rich portion of your blood is injected into the area that’s affected. In some cases, your doctor may use ultrasound guidance. This ensures proper needle placement.

 

 

What is involved in post-procedure care following PRP injections?

It’s normal to feel some discomfort in and around the injection site for a few days after your procedure.

  • Cold compresses may help to relieve your symptoms.
  • You’ll be instructed to stop using any anti-inflammatory medications.
  • Normal activities can be resumed but you should avoid any strenuous activities like heavy lifting or exercises.

 

 

What are the risks and complications of PRP injections?

There are very minimal risks associated with PRP injections. Some of the potential ones include:

  • Increased pain at the injection site;
  • Infection;
  • Damage to adjacent nerves or tissues;
  • Scar tissue formation;
  • Calcification at the injection site.

 

 

 

If you require expert platelet-rich plasma treatment, arrange a consultation with Mr Tibrewal via his Top Doctors profile.

By Mr Saket Tibrewal
Orthopaedic surgery

Mr Saket Tibrewal is a leading consultant trauma and orthopaedic knee surgeon based in Essex and London. He specialises in total knee replacementspartial knee replacementACL reconstruction alongside sports injuriescartilage regeneration and knee arthroscopy.  He practises privately in Essex at the Spire Hartswood Hospital, Nuffield Health Brentwood Hospital, Spire Wellesley Hospital & Springfield Hospital, as well as in London at the Basinghall Clinic and the Cromwell Hospital.  His NHS base is at Broomfield Hospital (Mid and South Essex NHS Foundation Trust).

Mr Tibrewal is highly qualified, with an MBBS from the Royal Free Hospital and University College Medical School at the University of London, and is triple fellowship trained at international centres of excellence in Sydney and Melbourne in Australia, as well as Oxford. He underwent specialist orthopaedic training on the prestigious Percivall Pott Rotation in London, and was awarded his FRCS from the Royal College of Surgeons in 2011. 

Mr Tibrewal's international sub-specialist training included comprehensive advanced experience in all aspects of knee surgery and he gained expertise in the use of computer navigation in Sydney. He then trained in complex arthroplasty and trauma reconstruction in Melbourne, and on his return to the UK he focused purely on knee surgery at the Nuffield Orthopaedic Centre in Oxford. There, he gained expertise in unicompartmental knee replacements (UKA).

Mr Tibrewal is one of only a few surgeons in his region solely dedicated to treating knee problems. He has extensive experience and one of the highest volume clinical practices covering all aspects of knee surgery and sports injuries. He strives to consistently deliver the same level of excellent care to every patient he treats. He provides a comprehensive specialist knee surgery service and is able to tailor any treatment he offers to best suit the individual needs of his patients. This results in them receiving bespoke personalised treatment that aims to return patients back to their day-to-day lives with the highest level of function as soon as possible. 

Mr Tibrewal was one of only two surgeons awarded the ESSKA-SLARD travelling fellowship in 2022. He visited the best hospitals and knee surgeons in Colombia, Peru, Chile, Brazil and Argentina where he was able to share his knowledge and experience, in addition to sitting on the expert panel for knee replacement surgery at the Argentinian Arthroscopy Association International Conference. He has also been awarded the BOTA-IOSUK Travelling Fellowship at Ganga Hospital and Breach Candy Hospital, the AO International Trauma Fellowship at Sunnybrook Hospital, Canada, the EFORT Travelling Fellowship at HUG, Switzerland, the HCA Foundation Scholarship in Melbourne and the BOA Travelling Fellowship in Endoklink, Germany. 

Mr Tibrewal's clinical research has been published in various peer-reviewed journals and he is an Associate Editor for the Journal of Clinical Orthopaedics & Trauma. He is a member of the General Medical Council (GMC), the British Medical Association (BMA) and the Medical Defence Union (MDU). He is also a member of the British Orthopaedic Association (BOA), the British Association for Surgery of the Knee (BASK) and the European Society for Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA). Further affiliations include membership of the American Academy of Orthopaedic Surgeons (AAOS), The Girdlestone Orthopaedic Society and The Magellan Orthopaedic Society.

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