Gamma Knife Radiosurgery: your questions answered

Written in association with: Mr John Yianni
Published: | Updated: 07/11/2023
Edited by: Aoife Maguire

Gamma Knife radiosurgery is a popular option used to treat brain tumours. Leading consultant neurosurgeon Mr John Yianni answers your commonly asked questions about the surgery, including how it works, its advantages over normal brain surgery and the recovery process.

 

 

What is Gamma Knife radiosurgery, and how does it work?

 

Gamma Knife radiosurgery is a non-invasive, highly precise form of radiation therapy primarily used to treat brain conditions such as tumours, vascular malformations, and trigeminal neuralgia. It utilises 192 focused beams of gamma radiation to target and destroy abnormal or diseased tissue within the brain.

 

This radiation is precisely aimed at the affected area, while sparing the surrounding healthy brain tissue. Gamma knife radiosurgery is typically performed in a single session and doesn't require an incision, making it a minimally invasive option.

 

What conditions can be treated with Gamma Knife radiosurgery?

 

Gamma Knife radiosurgery is effective intreating a variety of brain conditions, including the following:
 

 

The surgery can also used for specific cases of metastatic brain cancer and functional disorders such as cavernoma. The suitability for treatment is based on a variety of factors, such as the patient's condition and the size, location, and type of the brain abnormality.

 

What are the advantages of Gamma Knife radiosurgery over traditional brain surgery?

 

Gamma Knife radiosurgery offers several advantages over traditional open brain surgery. It is non-invasive, meaning it does not require an incision or the removal of the skull. As a result, it typically leads to shorter hospital stays, quicker recovery times, and reduced risk of complications.

 

Additionally, the precise nature of the treatment minimises damage to healthy brain tissue and often results in fewer side effects.

 

Is Gamma Knife radiosurgery painful, and what is the recovery process like?

 

Due to the non-invasive nature of Gamma Knife radiosurgery, it is not painfu, and patients are usually awake during the procedure. Local anaesthesia or mild sedation may be used during the procedure to ensure the patient’s comfort.

 

Recovery following the procedure is relatively quick, and the majority of patients can resume normal activities within a few days. Patients may experience some mild side effects such as headache or swelling. However, such side effects will typically ease off within a short time.

 

Are there any potential risks or side effects associated with Gamma Knife radiosurgery?

 

While Gamma Knife radiosurgery is considered safe and effective, it can pose the risk of some potential side effects, although they are generally mild and short-lived.

 

The surgery may provoke headaches, nausea, or fatigue. Additionally, there is a small risk of radiation-induced effects that can appear over time. Fortunately, however, the likelihood of such effects taking place is rare.

 

The specific risks and side effects posed can vary due to the patient's condition and the treatment plan, therefore it is essential to discuss these aspects with your doctor before undergoing the procedure.

 

 

 

If you would like to book a consultation with Mr Yianni, simply visit his Top Doctors profile today.

By Mr John Yianni
Neurosurgery

Mr John Yianni is a highly experienced consultant neurosurgeon based in Sheffield who specialises in functional neurosurgery and Gamma Knife surgery, including stereotactic radiosurgery and stereotactic radiotherapy using Gamma Knife. In addition to all aspects of neurosurgery, he is also an expert in the diagnosis and treatment of neurological-related disorders, such as dystonia, tremor and Parkinson’s disease, and has extensive experience with statistical package for the social sciences (SPSS) for complex analysis. Alongside his NHS work at Sheffield Teaching Hospital, Mr Yianni currently sees patients at the widely-acclaimed Thornbury Radiosurgery Centre.

Mr Yianni qualified from University College London in 1996, having become a member of the Royal College of Surgeons in 1992. He undertook his basic surgical training in Oxford and then went on to work as a clinical research fellow in neurosurgery with interest in stereotactic functional neurosurgery from 2001 to 2004 and was awarded a doctorate for his thesis. He acquired invaluable experience in this field as well as in framed and frameless stereotaxy.

He was later appointed a specialist neurosurgical trainee in neurosurgery from 2004 to 2009 and it was during this time that Mr Yianni became a fellow of the Royal College of Surgeons. He then worked as a fellow in stereotactic radiosurgery and functional neurosurgery and subsequently appointed as a consultant in 2011. With a specialist interest in stereotactic Gamma knife radiosurgery and stereotactic functional neurosurgery, Mr Yianni joined Thornbury Radiosurgery Centre, renowned for its high level of expertise in Gamma knife surgery.

Besides his neurosurgery practice, Mr Yianni holds an interest in research and regularly publishes his academic work in scientific peer-reviewed journals. He is also the Neurosurgery Theme Lead at Sheffield Clinical Research and Innovation Office.

View Profile

Overall assessment of their patients


  • Related procedures
  • Chronic headache
    Neuropathic pain
    Epilepsy
    Alzheimer's disease
    Movement disorders
    Transient ischaemic attack (TIA)
    Trapped nerve
    Scoliosis
    Spine fracture
    Rhizotomy
    This website uses our own and third-party Cookies to compile information with the aim of improving our services, to show you advertising related to your preferences as well analysing your browsing habits. You can change your settings HERE.