Managing cancer treatment-induced menopause

Written in association with: Dr Rene Roux
Published: | Updated: 27/11/2024
Edited by: Karolyn Judge

Cancer treatments such as chemotherapy, radiation and certain surgeries can lead to treatment-induced menopause, which occurs when cancer therapies interfere with the ovaries' function. This type of menopause can happen suddenly, especially in premenopausal women, and often brings more intense symptoms compared to natural menopause due to the abrupt loss of oestrogen.

Patient having cancer treatment, which can induce menopause symptoms.

 

What symptoms might patients experience?

 

Patients may experience common menopause symptoms such as hot flushes, night sweats, vaginal dryness, mood changes and fatigue. Symptoms can be more severe when menopause is induced rapidly by oncology treatments. These physical and emotional changes can add complexity to a patient's cancer treatment and recovery process, impacting their overall quality of life.

 

 

How can oncology-related menopause symptoms be managed?

 

Effective management of these symptoms involves a combination of medical treatment and supportive care. Hormone replacement therapy (HRT) is often avoided in women with certain hormone-sensitive cancers, so non-hormonal strategies become essential. These may include medications such as selective serotonin reuptake inhibitors (SSRIs) and gabapentin, which can help reduce hot flushes. Vaginal moisturisers and lubricants are recommended for managing vaginal dryness.

 

Lifestyle modifications are also important. Regular physical activity, a well-balanced diet and stress-reducing techniques like yoga and meditation can contribute to symptom relief. Cognitive behavioural therapy (CBT) has been shown to help manage emotional symptoms and improve quality of life.

 

 

What support options are available for patients with cancer treatment-induced menopause?

 

Patients can benefit from comprehensive support services, including counselling, support groups and specialised menopause clinics. These resources provide emotional support and practical advice tailored to managing menopause symptoms while undergoing cancer treatment. Working closely with a healthcare team ensures that symptom management strategies are both effective and safe within the context of ongoing cancer care.

By Dr Rene Roux
Medical oncology

Dr Rene Roux is a leading consultant medical oncologist with over 25 years’ experience who specialises in the diagnosis and systemic treatment of breast cancer and gynaecological cancers such as ovarian cancer. As a specialist, Dr Roux is renowned for her expertise and precision in the use of hormone therapy, chemotherapy, and targeted agents (including PARP inhibitors and CDK4/6 inhibitors) for cancer management.

She consults privately at Nuffield Health The Manor Hospital, Oxford, at The Chiltern Hospital, and at GenesisCare Oxford. As well as this, Dr Roux also manages a busy NHS practice at Oxford University Hospitals, where she serves as operational lead and as chair for the systemic anti-cancer treatment service in addition to her consultant duties.

Dr Roux originally qualified from the University of Cape Town in 1997. She then trained in London, in internal medicine at St Mary’s Hospital and in medical oncology at The Royal Marsden, before going on to complete formal research at the prestigious Institute of Cancer Research. Dr Roux accomplished her higher specialist training in medical oncology at The Royal Free, University College Hospital and Mount Vernon Hospital, and was awarded membership to the Royal College of Physicians in 2003. She joined Oxford University Hospitals as a consultant in 2016.

Alongside her clinical practice, Dr Roux is a principal investigator for multiple national and international clinical trails in breast cancer, ovarian cancer, endometrial cancer, and advanced cervical cancer. She is the gynaecological sub-specialty lead for the Thames Valley Cancer Research Network and the appointed oncology lead for the Oxford Specialist Oncology Menopause multidisciplinary team, and is also a member of various professional organisations including the British Gynaecological Cancer Society.

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