Semaglutide and obesity: A new era in weight management

Written in association with: Dr Oliver Large
Published: | Updated: 29/11/2024
Edited by: Conor Lynch

Semaglutide has emerged as a groundbreaking medication in the fight against obesity, offering a promising solution for individuals struggling to achieve sustainable weight loss. Originally developed to treat type 2 diabetes, semaglutide has shown significant efficacy in promoting weight loss and improving overall health.

What is semaglutide?

Semaglutide belongs to a class of medications known as GLP-1 receptor agonists. It mimics a hormone called glucagon-like peptide-1, which regulates appetite and blood sugar levels. By targeting the brain's hunger centers, semaglutide reduces appetite and increases feelings of fullness, helping individuals eat less and make healthier food choices.

 

Semaglutide for obesity

In clinical trials, semaglutide has demonstrated remarkable results for individuals with obesity. Studies have shown that patients using semaglutide alongside lifestyle modifications lost an average of 15-20% of their body weight over a year. This level of weight loss surpasses what is typically achievable with diet and exercise alone, making semaglutide a game-changer for those who struggle to manage their weight.

 

The medication is administered via a weekly injection, making it convenient for long-term use. It is generally well-tolerated, though some users may experience mild side effects such as nausea, diarrhoea, or constipation, particularly during the initial weeks of treatment.

 

Beyond weight loss

The benefits of semaglutide extend beyond weight reduction. Losing significant weight can lead to improvements in various obesity-related conditions, such as type 2 diabetes, hypertension, sleep apnoea, and joint pain. Additionally, weight loss can enhance mental health, self-esteem, and overall quality of life.

 

The importance of comprehensive care

While semaglutide offers a powerful tool for weight management, it works best when combined with a comprehensive approach that includes dietary changes, regular physical activity, and behavioral support. It’s not a standalone cure but a facilitator of sustainable lifestyle changes.

 

For individuals considering semaglutide, consulting a healthcare professional is essential to determine its suitability and develop a personalised plan for achieving long-term health and weight management goals. This innovative medication marks a significant step forward in addressing the global obesity epidemic.

By Dr Oliver Large
GP (general practitioner)

Dr Oliver Large is a highly experienced GP who specialises in mens health, travel medicine, and weight loss. He is also the medical director of the 222 Healthcare clinic

With a strong commitment to innovation in healthcare, he has spent the last eight years leading advancements in digital health, playing key roles in reshaping primary care services to focus more on person-centred care. Dr Large previously held the position of UK medical director at one of Europe’s largest digital health companies, after which he helped a Danish company (Embla) to bring their premium online weight loss clinic to the UK.

His experience in these roles inspired his belief that exceptional healthcare requires seamless integration of both in-person and digital access to doctors. To put this vision into practice, he founded 222 Healthcare, a private GP clinic based in Stokenchurch, High Wycombe, Buckinghamshire. At 222 Healthcare, Dr Large and his team offer a wide range of services, including extended GP consultations, travel vaccinations, and women’s health care options.

By offering 30-minute appointments—significantly longer than typical NHS consultations—the clinic ensures that patients have ample time to discuss their concerns in depth. Dr Large is passionate about giving patients the time and attention they need for effective diagnosis and treatment planning, striving to provide a more personal, attentive, and comprehensive approach to healthcare.

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