The health benefits of weight loss in breast cancer patients

Written in association with: Dr Shiroma De Silva-Minor
Published: | Updated: 28/06/2023
Edited by: Conor Dunworth

Dr Shiroma De Silva-Minor is a consultant medical and clinical oncologist, with extensive experience in the treatment of breast cancer. In her latest online article, Dr De Silva-Minor explains the numerous health benefits that weight loss can provide for breast cancer patients.

 

What are the health benefits of weight loss for breast cancer patients?

Reduced risk of cancer recurrence:

Obesity is associated with an increased risk of breast cancer recurrence and mortality. Weight loss may help reduce this risk by reducing the production of oestrogen, which can fuel the growth of hormone receptor-positive cancers in particular.  

 

Improved response to cancer treatments:

Some studies have suggested that overweight and obese breast cancer patients may not respond as well to certain cancer treatments. For example, anti-oestrogen therapy, which is commonly used to treat hormone receptor-positive breast cancer, may be less effective in obese patients. Obesity is associated with higher levels of circulating oestrogen, which can promote the growth of hormone receptor-positive breast cancer cells. Research also suggests that drug metabolism and absorption rates may be different in obese patients.  Weight loss may improve the effectiveness of these treatments and improve overall outcomes.

 

Improved cardiovascular health:

Weight loss can reduce the risk of cardiovascular disease, which is a leading cause of death in breast cancer survivors, especially as some treatments for breast cancer such as anthracycline chemotherapy and radiotherapy (particularly to the left breast or chest wall) can increase risk of heart disease. Other cardiovascular disease risk factors, such as high blood pressure and high cholesterol, can also be improved with weight loss.

 

Improved quality of life:

Weight loss can improve overall quality of life by reducing fatigue, improving mood, and increasing energy levels. This can be especially important for breast cancer patients, who may experience fatigue and other side effects of cancer treatment.

 

Reduced risk of other health problems:

Obesity is associated with an increased risk of many chronic health problems, such as Type 2 diabetes, arthritis, and sleep apnoea. Weight loss can reduce the risk of these problems and improve overall health.

 

It's important to note that weight loss should be approached in a healthy, sustainable way, with realistic goals and in conjunction with discussions and support from your doctor. Crash diets and rapid weight loss can be harmful and may not provide long-term benefits or be sustainable. A doctor or registered dietitian can help develop a safe and effective weight loss plan for breast cancer patients.

 

Dr Shiroma De Silva-Minor is a highly-experienced consultant medical and clinical oncologist based in London, Oxford & Swindon. If you would like to book a consultation with Dr De Silva-Minor you can do so today via her Top Doctors profile. 

By Dr Shiroma De Silva-Minor
Clinical oncology

Dr Shiroma De Silva-Minor is an accomplished and experienced consultant breast oncologist who specialises in breast cancer (both male and female), breast screening, chemotherapy, radiotherapy, immunotherapy, intraoperative radiation therapy, inflammatory breast cancers, HER2 positive disease, triple-negative breast cancers and breast cancer in pregnancy.

Dr De Silva-Minor oversees the entire (non-surgical) breast cancer pathway so she can advise on all aspects of treatment, including genetic counselling and testing, systemic (chemo) therapy, radiotherapy, and lifestyle factors in optimising health and minimising disease recurrence.  Dr De Silva-Minor was a Consultant Clinical Oncologist at the Oxford University Hospitals NHS Foundation Trust from 2008 till 2024 and recently left the NHS. The doctor now  has a private practise at the Cromwell Hospital in London and GenesisCare in Oxford.

Dr De Silva-Minor, whose clinical expertise is in the treatment of early, metastatic and recurrent breast cancer, notably obtained her first medical qualification in 1995, with her medical doctorate from the prestigious Cardiff-based University of Wales College of Medicine. In 1999, Dr De Silva-Minor was awarded the Membership of the Royal College of Physicians (UK).  Dr De Silva-Minor undertook  specialist oncology training at centres of oncological excellence in London, including The Middlesex Hospital, The Royal Free Hospital, as well as The Royal Marsden Hospital, amongst others.

In 2003, Dr De Silva-Minor was awarded the Fellowship of the Royal College of Radiologists and was also recognised as a clinical oncology specialist on the General Medical Council's register in 2007. 

Dr De Silva-Minor has published extensively in peer-reviewed journals. During a Fellowship in head and neck radiation oncology at The Princess Margaret Hospital in Toronto, Canada, Dr De Silva-Minor was awarded the Prize for Academic Excellence by the Princess Margaret Hospital and the University of Toronto for her research into the use of PETCT scans (Positron Emission Tomography) when identifying head and neck tumours for treatment with radiotherapy.   Dr De Silva-Minor was a member of the breast cancer expert panel for the National Institute of Health and Clinical Excellence (NICE), updating clinical guidelines on breast cancer management.

Dr De Silva-Minor is also collaborating on a metanalysis with the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) to bring together the research on radiotherapy clinical trials to better understand how to optimally treat breast cancer patients with radiotherapy.  Dr De Silva-Minor is a member of the Advisory Board on Cancer in Pregnancy (ABCIP), an international panel of experts in managing breast cancer in pregnancy. 

Dr De Silva-Minor is a passionate advocate for empowering her patients to be involved in their management decisions. Treatment is completely bespoke to individual patients, their specific tumour subtype, taking into consideration the individual's beliefs, wishes and personal circumstances.

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