Understanding GI tract cancers: Diagnosis to treatment

The intricate network of the gastrointestinal (GI) tract, responsible for digestion and nutrient absorption, is susceptible to a spectrum of cancers. These malignancies can arise anywhere along the GI tract, from the oesophagus to the rectum, presenting diverse challenges in diagnosis and management. Understanding the nuances of GI tract cancers, including their types, symptoms, risk factors, and treatment modalities, is paramount for effective intervention and improved outcomes. In his latest online article, Dr Cheng Boon gives us his insights.

Types of GI tract cancers:

Oesophageal cancer: This cancer manifests in the oesophagus, often revealing symptoms at advanced stages such as dysphagia (difficulty swallowing), unintentional weight loss, and chest pain.

Gastric (Stomach) cancer: Gastric cancer can develop in any part of the stomach and is linked to factors like chronic gastritis, Helicobacter pylori infection, smoking, and certain dietary patterns.

Colorectal cancer: Among the most prevalent GI tract cancers, colorectal cancer affects the colon or rectum. Symptoms may include alterations in bowel habits, rectal bleeding, abdominal discomfort, and unexplained weight loss.

Liver cancer: Hepatocellular carcinoma (HCC) predominates in liver cancer cases. Risk factors include chronic hepatitis B or C infections, excessive alcohol consumption, non-alcoholic fatty liver disease, and specific genetic predispositions.

Pancreatic cancer: Typically diagnosed in advanced stages, pancreatic cancer presents challenges in treatment. Symptoms such as abdominal pain, jaundice, weight loss, and digestive disturbances may indicate its presence.

Gallbladder and biliary tract cancer: Originating from gallbladder or bile duct tissues, these cancers, while relatively rare, may provoke symptoms like jaundice, abdominal pain, and nausea.

Symptoms and risk factors:

Common symptoms of GI tract cancers include persistent abdominal discomfort, changes in bowel habits, unexplained weight loss, difficulty swallowing, and jaundice.

Risk factors include age, family history, smoking, alcohol consumption, obesity, inflammatory conditions, and certain infections like H. pylori and hepatitis viruses.

Diagnosis and treatment:

Early detection significantly influences the prognosis of GI tract cancers. Diagnostic methods include endoscopy, imaging tests, and biopsies.

Treatment modalities range from surgery to chemotherapy, radiation therapy, and targeted therapy, tailored to the cancer type, stage, and patient's overall health.

Prevention and outlook:

While not all GI tract cancers are preventable, adopting a healthy lifestyle and undergoing regular screenings can mitigate risks. By fostering awareness, early detection, and comprehensive care, individuals can navigate GI tract cancers with greater resilience, enhancing both digestive health and overall well-being.

Dr Cheng Boon is an esteemed medical oncologist. You can schedule an appointment with Dr Boon on his Top Doctors profile.