Understanding inflammatory bowel disease: Symptoms, diagnosis, and treatment

Written in association with: Dr James Evans
Published: | Updated: 07/11/2024
Edited by: Conor Lynch

Inflammatory bowel disease (IBD) is a term used to describe two chronic conditions that cause inflammation of the gastrointestinal tract: Crohn's disease and ulcerative colitis. These conditions can significantly impact a person's quality of life, causing symptoms such as abdominal pain, diarrhoea, fatigue, and weight loss. Both diseases are characterised by periods of flare-ups and remission, where symptoms worsen and then improve, respectively.

Crohn's disease can affect any part of the digestive system, from the mouth to the anus, but it most commonly impacts the small intestine and colon. Ulcerative colitis, on the other hand, primarily affects the colon (large intestine) and rectum.

 

The exact cause of IBD is still unclear, but it is believed to involve a combination of genetic factors, an abnormal immune system response, and environmental triggers. IBD is more common in people with a family history of the condition and tends to develop in young adults, though it can occur at any age.

 

Diagnosing IBD

Diagnosing IBD involves a thorough evaluation, including medical history, physical examination, blood tests, stool samples, and imaging studies such as colonoscopy or endoscopy. These tests help doctors assess the extent and severity of the inflammation, which is essential for developing an effective treatment plan.

 

Treatment

Treatment for IBD focuses on reducing inflammation, managing symptoms, and improving quality of life. Medications are the first line of treatment and may include anti-inflammatory drugs, immune system suppressors, and biologics (drugs that target specific proteins involved in the immune response).

 

In some cases, antibiotics may be prescribed to treat or prevent infections. For severe cases that don’t respond to medication, surgery may be necessary to remove damaged portions of the intestine or colon.

 

Management

Living with IBD requires a multidisciplinary approach, including regular monitoring by a gastroenterologist, dietary adjustments, and stress management. While there is currently no cure for IBD, advancements in treatment have significantly improved the prognosis for many patients, allowing them to maintain an active and fulfilling lifestyle despite the condition.

By Dr James Evans
Gastroenterology

Dr James Evans is a consultant gastroenterologist at One Hatfield Hospital and OSD Healthcare in Hemel Hempstead seeing patients from all across Hertfordshire, Bedfordshire and North London.
 
He specialises in endoscopy, colonoscopy, bowel cancer, inflammatory bowel disease (IBD), acid reflux, difficulty swallowing and irritable bowel syndrome (IBS). Dr Evans is known for his proficiency in diagnostic and therapeutic endoscopy and managing the Upper GI cancer service and physiology testing service for reflux and swallowing issues.
 
In addition to his clinical work, Dr Evans serves as the Trust Lead for Upper GI Cancer, and Lead for investigating Cancer of Unknown Primary source (CUP) at East & North Herts with clinics in Stevenage, Welwyn and Hertford. Dr Evans is a member of the Regional Upper GI Cancer Alliance and also heads the Regional Laser service for oesophageal cancer.
 
Dr Evans completed his BSc in Neurosciences at Sussex University in 1998 and graduated from Leicester/Warwick Medical School in 2006, earning recognition with a Clinical Medicine prize. His speciality training occurred between 2012 and 2018 in North West London, at esteemed centres such as St. Marks, St. Mary’s, and Royal London Hospitals. In 2018, Dr Evans obtained a Ph.D. from Queen Mary University of London for research focused on Barrett’s oesophagus biology and its connection to cancer development. His research contributions include publications in peer-reviewed scientific journals and presentations at international meetings.
 
Dr Evans is actively engaged in medical education and training and has previously served as the Endoscopy training lead for East & North Herts NHS Trust. He regularly provides education through regional JAG accredited endoscopy training courses. Dr Evans’ dedication is evident in his commitment to patient care and medical education in the field of gastroenterology.

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