What is being analysed?

The analysis centres around measuring the levels of methylmalonic acid (MMA) in the blood. methylmalonic acid is a crucial marker used to assess vitamin B12 status and diagnose related disorders.

What does the result mean?

The result of the MMA analysis provides insights into vitamin B12 deficiency. Elevated levels may indicate a malfunction in the metabolism of B12, potentially leading to various health issues.

Why do the analysis?

MMA analysis is essential for diagnosing and monitoring vitamin B12 deficiency, which can lead to anaemia, neurological problems, and other complications. It aids in early intervention and appropriate management.

When to do the analysis?

The analysis is recommended when there are signs of vitamin B12 deficiency, such as fatigue, weakness, pale skin, and neurological symptoms. It is also crucial for individuals with certain risk factors like pernicious anaemia or gastrointestinal disorders.

What sample is required?

A blood sample is required for the MMA analysis. This sample is typically drawn from a vein in the arm.

Is any type of prior preparation necessary?

No specific preparation is usually required. However, it is essential to inform the doctor about any medications or supplements being taken, as they can influence the results.

How is it used?

The MMA analysis is conducted through liquid chromatography-mass spectrometry (LC-MS) or other sophisticated techniques, ensuring accurate measurement of methylmalonic acid levels in the blood.

What are the normal values?

These values can slightly vary between laboratories. Interpreting results in conjunction with clinical context is crucial for an accurate diagnosis.

What does it mean to have altered values?

Elevated methylmalonic acid levels suggest a potential vitamin B12 deficiency. This deficiency can lead to anaemia and neurological problems. Early detection through MMA analysis allows for timely intervention and effective management to prevent complications.