Dr Crispin Hiley

Professional statement

Dr Crispin Hiley is an internationally recognised expert in oncology, bringing cutting-edge science and compassionate care to his patients. Privately practising at London Cromwell Hospital, LOC (Leaders in Oncology Care) at The Harley Street Clinic - HCA Healthcare and Proton International @ UCLH, he specialises in all the different kinds of lung cancer and also possesses a significant amount of expertise in chemotherapy, cancer immunotherapy, radiotherapy and proton beam therapy, as well as mesothelioma, amongst many others.

As an Associate Professor in Oncology at University College London and a Consultant Oncologist at University College London Hospital, Dr Hiley is at the forefront of cancer treatment and research. He also serves as the Clinical Director for Lung Cancer at GenesisCare UK, which offers private healthcare across 14 specialist centres in the UK.

Dr Hiley is dedicated to providing personalised care tailored to each patient's unique needs. He is available for private consultations in London and offers comprehensive chemotherapy and radiotherapy services across the UK. For patients who prefer treatment at home, he can arrange for chemotherapy to be administered where appropriate.

Specialising in non-surgical treatments for lung cancer, Dr. Hiley is an expert in chemotherapy, immunotherapy and targeted therapy, alongside radiotherapy, including advanced techniques such as volumetric arc therapy (VMAT), intensity modulated radiotherapy (IMRT) and image guided radiotherapy (IGRT) as well as proton therapy and stereotactic radiotherapy (SBRT).

Through his work in clinical trials and translational research Dr Hiley has published important research in the mechanism of resistance to EGFR inhibitors such as Osimertinin and immunotherapy such as Atezolizumab and Pembrolizumab.

As the UCLH Lead for Lung Proton Therapy, Dr Hiley was the first oncologist in the UK to treat lung cancer patients with this cutting-edge technology. He is also the chief investigator of the HIT-MESO trial, which explores the use of proton beam radiotherapy for mesothelioma patients. Through his role with Proton International@UCLH, Dr Hiley offers advanced proton therapy treatments for private patients.

Dr Hiley’s expertise extends beyond lung cancer. He specializes in stereotactic radiotherapy (SBRT) for oligo metastatic and oligo progressive diseases in various cancers, including breast, prostate and colorectal, gynaecological, sarcoma and lung.

He utilises state-of-the-art technology, including MRI-guided SABR with the ViewRay MRIdian system, to treat challenging tumour lesions. Additionally, he offers reirradiation therapy for patients who have previously undergone radiotherapy.

Dr Hiley graduated with honours from the University of Manchester in 2005 and has trained at prestigious institutions such as the Christie Hospital, MD Anderson Cancer Centre, Kings College, and the Royal Marsden. He holds a PhD from the University of London and has completed postdoctoral research fellowships at the Francis Crick Institute and the UCL Cancer Institute.

As a consultant since 2018, Dr Hiley leads the clinical oncology lung team at UCLH. His roles include UCLH Lead for Lung Proton Therapy, Deputy Lead of Clinical Trials for the CRUK Lung Cancer Centre of Excellence and NIHR Clinical Research Network Specialty Research Lead in Radiotherapy for North London.

He heads a research group focused on understanding resistance to cancer treatments and is the principal investigator for numerous clinical trials. His work has been published in leading journals such as NEJM, The Lancet, Nature, and Cell. Dr Hiley also contributed to the Royal College of Radiologists Consensus Statement on Radiotherapy for Lung Cancer which defines the standard of practice in the UK.

For more details and to book a consultation with Dr Hiley, you can arrange a consultation with him at London Cromwell Hospital or at LOC (Leaders in Oncology Care) at The Harley Street Clinic - HCA Healthcare. Just select the location and time in the 'REQUEST APPOINTMENT NOW' box on the right-hand side of this page.

Dr Crispin Hiley combines world-class expertise with compassionate care to provide the best possible outcomes for his patients. If you’re seeking a top oncologist in the UK, he is here to help.