Radiotherapy for prostate cancer: what to know

Written in association with: Professor Heather Payne
Published: | Updated: 23/09/2024
Edited by: Conor Lynch

Radiotherapy is a common and effective treatment for prostate cancer, utilising high-energy radiation to target and destroy cancer cells. This treatment is typically considered for patients with localised or locally advanced prostate cancer, where the cancer is confined to the prostate or nearby tissues. Radiotherapy offers a non-invasive alternative to surgery and is often chosen based on factors like the stage of cancer, overall health, and patient preference.

 

There are two main types of radiotherapy used in prostate cancer treatment: external beam radiotherapy (EBRT) and brachytherapy. Here to explain more is esteemed clinical oncologist, Professor Heather Payne

External beam radiotherapy (EBRT)

EBRT is the most widely used form of radiotherapy for prostate cancer. It involves directing radiation beams at the prostate gland from outside the body using a machine called a linear accelerator. Advances in EBRT, such as intensity-modulated radiation therapy (IMRT) and image-guided radiation therapy (IGRT), have increased precision, minimising damage to surrounding healthy tissues like the bladder and rectum. Treatments are typically administered five days a week over several weeks.

 

Brachytherapy

Brachytherapy, or internal radiotherapy, involves placing radioactive seeds directly into or near the prostate gland. There are two types: low-dose-rate (LDR) brachytherapy, where seeds release radiation over weeks or months, and high-dose-rate (HDR) brachytherapy, where temporary sources deliver a high dose of radiation in a shorter period. Brachytherapy is highly effective for early-stage prostate cancer and can be combined with EBRT for more advanced cases.

 

Side effects of radiotherapy for prostate cancer can include urinary issues, bowel problems, and erectile dysfunction, though advancements in techniques have reduced these risks. Most side effects are temporary, but some may persist long-term, requiring management.

 

Radiotherapy offers a high cure rate for localized prostate cancer and can also be used in combination with hormone therapy for more advanced stages. Patients should discuss the benefits and potential side effects with their healthcare team to determine the best treatment plan tailored to their individual needs.

By Professor Heather Payne
Clinical oncology

Professor Heather Payne is a highly regarded clinical oncologist based in London, specialising in the treatment of various urological cancers. With a primary focus on prostate cancer, her areas of expertise also encompass radiotherapy, hormone therapy, image-guided radiotherapy (IGRT), chemotherapy, and brachytherapy. Beyond prostate cancer, Professor Payne is well-versed in managing bladder cancer, kidney cancer, penile cancer, and testicular cancer, showcasing her comprehensive approach to urological oncology.
 
Professor Payne underwent her training at St Mary's Hospital, developing a strong foundation for her subsequent professional endeavours. Currently, she operates within a multidisciplinary team at her bustling practice, where her work extends to pioneering initiatives in the field. Notably, her research contributions encompass hormone therapy, proton beam therapy for prostate cancer, and the innovative use of high-dose-rate brachytherapy in prostate cancer treatment.
 
In addition to her clinical and academic roles, Professor Payne actively engages in research, reflecting her commitment to advancing the field of oncology. Her research interests include sensitisation of hormones and radiotherapy, predictive indices for bowel toxicity with radiotherapy, proton beam therapy for prostate cancer and supporting men in decision-making processes related to prostate cancer. This dedication to research aligns with her holistic approach to patient care.
 
Professor Payne's contributions extend beyond the clinical and research realms. As the chair of the British Uro-oncology Group (BUG) and a trustee of the Prostate Cancer Research Centre, she holds leadership roles within key organisations dedicated to urological oncology. Her reputation for expertise and her compassionate approach make her a trusted figure, particularly in helping patients navigate challenging treatment decisions.

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