What is being analysed?

Aldolase is an enzyme that plays a crucial role in glycolysis, the process by which cells break down glucose to produce energy. The analysis of aldolase levels in the blood helps assess muscle and liver function, making it a valuable diagnostic tool for various medical conditions.

What does the result mean?

Elevated aldolase levels may indicate muscle or liver damage, inflammation, or certain autoimmune diseases. Conversely, lower-than-normal levels might suggest a deficiency in aldolase production. Interpretation should be done in conjunction with other clinical and laboratory findings for a comprehensive diagnosis.

Why do the analysis?

Aldolase analysis aids in diagnosing and monitoring conditions such as muscular dystrophy, dermatomyositis, and autoimmune hepatitis. It provides valuable insights into the extent of tissue damage and helps guide treatment decisions.

When to do the analysis?

Aldolase analysis is typically ordered when a patient exhibits symptoms such as muscle weakness, pain, or elevated liver enzymes. It is also used to monitor disease progression or the effectiveness of ongoing treatments.

What sample is required?

A blood sample is collected through a routine blood draw to measure aldolase levels accurately. The procedure is minimally invasive and can be performed in most clinical settings.

Is any type of prior preparation necessary?

No special preparation is required before the aldolase analysis. However, it is essential to inform your doctor about any medications, supplements, or underlying medical conditions that might influence the results.

How is it used?

Aldolase analysis is an integral part of the diagnostic process. It helps doctors pinpoint the underlying cause of symptoms and provides a baseline for monitoring treatment effectiveness. Additionally, aldolase levels may be used alongside other biomarkers for a more comprehensive assessment.

What are the normal values?

Normal aldolase values can vary slightly between laboratories. Generally, normal levels range from 1 to 8 U/L (units per litre). Deviations from this range may indicate an underlying health issue.

What does it mean to have altered values?

Elevated Aldolase: Increased levels may suggest muscle damage (myopathy), liver diseases, or inflammatory conditions. Further diagnostic tests may be needed to determine the specific cause.

Decreased Aldolase: Low levels may be associated with a rare condition known as aldolase B deficiency. However, low aldolase alone is not diagnostic, and additional investigations are necessary for a conclusive diagnosis.

Aldolase Values in Table Format

Understanding aldolase levels is vital in diagnosing and managing various medical conditions. You should consult with a specialist for accurate interpretation and guidance based on your specific health concerns.