Catecholamines test
What is being analysed?
Catecholamines are neurotransmitters and hormones produced by the adrenal glands, which include dopamine, norepinephrine, and epinephrine. The analysis typically involves measuring the levels of these substances in the blood or urine.
What does the result mean?
The results of catecholamine analysis provide insight into the functioning of the sympathetic nervous system and adrenal gland activity. Abnormal levels may indicate various medical conditions such as pheochromocytoma, neuroblastoma, or autonomic dysfunction.
Why perform the test?
Catecholamine analysis is performed to diagnose and monitor conditions related to adrenal gland function, such as hypertension, sweating, palpitations, and anxiety. It helps in identifying tumours or disorders affecting catecholamine production and metabolism. Catecholamine analysis is typically requested when symptoms suggestive of excessive catecholamine activity are present.
What sample is required?
Blood and urine samples are commonly used for catecholamine analysis. Blood samples are often collected via venipuncture, while urine samples are collected over a 24-hour period for accurate measurement.
Is any prior preparation necessary?
Prior preparation may be necessary depending on the specific test and the healthcare provider's instructions. Patients may be asked to avoid certain medications, foods, or activities that could interfere with test results.
What are the normal values?
|
Catecholamine |
Normal Range (Blood) |
Normal Range (Urine) |
|---|---|---|
|
Dopamine |
0-20 ng/mL |
0-100 mcg/24h |
|
Norepinephrine |
70-750 pg/mL |
15-100 mcg/24h |
|
Epinephrine |
10-50 pg/mL |
1-20 mcg/24h |
This table provides the normal ranges for catecholamines in both blood and urine samples for reference:
These values may vary slightly depending on the laboratory and testing methods used. Abnormal results should always be interpreted in conjunction with clinical symptoms and additional diagnostic tests for accurate diagnosis and management.
What does having elevated values mean?
Elevated levels of catecholamines in the blood or urine may indicate conditions such as pheochromocytoma, neuroblastoma, or autonomic dysfunction. Conversely, low levels may suggest adrenal insufficiency or certain neurological conditions.