What is being analysed?

Coeliac disease tests primarily analyse the presence of specific antibodies in the blood that indicate an immune response to gluten, a protein found in wheat, barley, and rye.

What does the result indicate?

A positive result suggests the presence of coeliac disease or gluten intolerance. Negative results generally indicate the absence of a significant immune response to gluten.

Why is the analysis performed?

The analysis is performed to diagnose coeliac disease or to confirm suspicions based on symptoms like chronic diarrhoea, abdominal pain, fatigue, and weight loss.

When is the analysis recommended?

Coeliac disease tests are recommended when individuals exhibit symptoms suggestive of coeliac disease or when there is a family history of the condition.

What sample is required?

The analysis typically requires a blood sample, obtained through a simple blood draw.

Is any prior preparation necessary?

No specific prior preparation is typically required for coeliac disease blood tests.

How are the results used?

Results are used by healthcare providers to confirm or rule out coeliac disease and to guide further diagnostic and treatment decisions.

What are the normal values?

What does having altered values indicate?

• Elevated levels of IgA anti-tissue transglutaminase (tTG) antibodies or IgA anti-endomysial antibodies (EMA) suggest a high likelihood of coeliac disease.
• Low levels of total serum IgA may affect the accuracy of IgA-based tests and may indicate a deficiency that needs to be addressed.

These values, when outside the normal range, typically indicate an abnormal immune response to gluten, which is characteristic of coeliac disease.

By understanding these tests and their results, individuals and doctors can better manage and diagnose coeliac disease, leading to appropriate treatment and improved quality of life.