D-dimer
What is analysed?
D-dimer analysis focuses on measuring the levels of a specific protein fragment called D-dimer in the blood.
What does the result mean?
The results of a D-dimer analysis can indicate the presence or absence of blood clotting and fibrinolysis. Elevated levels may suggest the formation and breakdown of blood clots.
Why perform the analysis?
The D-dimer analysis is crucial in diagnosing and monitoring conditions related to blood clotting, such as deep vein thrombosis (DVT), pulmonary embolism, and disseminated intravascular coagulation (DIC). It helps in assessing the risk of these conditions.
When to perform the analysis?
D-dimer analysis is often conducted when there is suspicion of abnormal blood clotting, such as in cases of unexplained swelling, chest pain, or difficulty breathing. It is also used for post-surgery monitoring and in assessing certain medical conditions.
Required sample:
A blood sample is required for D-dimer analysis. Typically, a venous blood sample is collected for laboratory testing.
Preparation requirements:
Usually, there are no specific preparations needed before a D-dimer analysis. However, it is essential to inform healthcare providers about any medications or medical conditions that might affect the results.
How is it conducted?
The D-dimer analysis involves drawing a blood sample, which is then processed in a laboratory. Various methods, including enzyme-linked immunosorbent assay (ELISA), are employed to measure D-dimer levels accurately.
Normal values:
Age Group |
Normal D-dimer Levels (μg/mL) |
Adults |
Below 0.5 |
Elderly |
Slightly higher |
Children |
Variable |
Significance of abnormal values:
Elevated D-dimer levels may indicate increased blood clotting activity, but it does not specify the location or cause of the clot. Further diagnostic tests are often required to determine the underlying condition.