Diabetic retinopathy

What is diabetic retinopathy?

Diabetic retinopathy is a complication of diabetes that affects the eye and can severely damage vision, even causing blindness if left untreated. The retina is the layer of cells on the back wall of the inside of the eye. These cells, known as photoreceptor cells, are light-sensitive and can be divided into cones and rods.

Light enters through the front of the eye and is focused by the lens onto the retina, stimulating the cells, which triggers a nerve signal to be sent to the brain. The brain then forms an image, based on the signal sent from the retina, making the retina crucial to our ability to see.

To do its job, the retina needs a constant supply of blood to bring it oxygen and nutrients. If diabetes is not well-managed, the blood sugar level rises to dangerous levels, and one effect this can have is to cause the tiny blood vessels supplying the retina to bulge and leak and reduce the level of oxygen reaching the photoreceptor cells.

What are the symptoms of diabetic retinopathy?

Diabetic retinopathy usually causes no symptoms in the early stages, which means it often progresses enough to affect vision. When this happens, certain symptoms may manifest:

  • Blurry vision
  • Progressive loss of vision
  • Floaters
  • Shadows or missing areas of vision
  • Difficulty to see during the night
  • Soreness and redness in the eye

What is more alarming is that in some cases, it can progress without warning signs, so for diabetic patients it is important to have regular eye exams.

How does diabetes affect the eye?

Over time, a persistently high blood sugar level caused by diabetes can damage the blood vessels that supply the retina with oxygen and nutrients. There are three main stages to this:

  • Background retinopathy – the capillaries in the eye develop tiny bulges and may leak slightly, but vision is largely unaffected.
  • Pre-proliferative retinopathy – damage to the blood vessels becomes more pronounced, with significant bleeding into the eye.
  • Proliferative retinopathy – scar tissue and new, fragile blood vessels develop on the retina as the body attempts to maintain the blood supply to the retina. However, these bleed easily, and cause vision loss.

The probability of suffering from diabetic retinopathy is greater if the patient:

  • Has suffered diabetes for many years
  • Has inadequate control of their blood glucose
  • Smokes
  • Suffers from high blood pressure
  • Is obese

Can diabetic retinopathy be prevented?

To avoid diabetic retinopathy, it is essential for diabetic patients to keep their blood glucose, blood pressure and cholesterol under control. Smoking is strongly discouraged.

What is the treatment for diabetic retinopathy?

Patients suffering from the early form of the disease may not require treatment, although it is essential to manage diabetes and monitor the progression of the retinopathy.

For diabetic retinopathy that is affecting vision, the following treatments may be recommended:

  • Laser treatment (photocoagulation) – a laser is used to treat the abnormal blood vessels at the back of the eye in proliferative retinopathy. It usually doesn’t improve vision, but can prevent the condition from worsening.
  • Eye injections
  • Vitrectomy – surgery to remove the vitreous humour (jelly-like substance that fills the eye), performed when there has been significant bleeding into the eye and it is also a useful technique to prevent retinal detachment.
 10-30-2023
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Diabetic retinopathy

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Mrs Kapka Nenova - Ophthalmology

Created on: 03-04-2013

Updated on: 10-30-2023

Edited by: Conor Lynch

What is diabetic retinopathy?

Diabetic retinopathy is a complication of diabetes that affects the eye and can severely damage vision, even causing blindness if left untreated. The retina is the layer of cells on the back wall of the inside of the eye. These cells, known as photoreceptor cells, are light-sensitive and can be divided into cones and rods.

Light enters through the front of the eye and is focused by the lens onto the retina, stimulating the cells, which triggers a nerve signal to be sent to the brain. The brain then forms an image, based on the signal sent from the retina, making the retina crucial to our ability to see.

To do its job, the retina needs a constant supply of blood to bring it oxygen and nutrients. If diabetes is not well-managed, the blood sugar level rises to dangerous levels, and one effect this can have is to cause the tiny blood vessels supplying the retina to bulge and leak and reduce the level of oxygen reaching the photoreceptor cells.

What are the symptoms of diabetic retinopathy?

Diabetic retinopathy usually causes no symptoms in the early stages, which means it often progresses enough to affect vision. When this happens, certain symptoms may manifest:

  • Blurry vision
  • Progressive loss of vision
  • Floaters
  • Shadows or missing areas of vision
  • Difficulty to see during the night
  • Soreness and redness in the eye

What is more alarming is that in some cases, it can progress without warning signs, so for diabetic patients it is important to have regular eye exams.

How does diabetes affect the eye?

Over time, a persistently high blood sugar level caused by diabetes can damage the blood vessels that supply the retina with oxygen and nutrients. There are three main stages to this:

  • Background retinopathy – the capillaries in the eye develop tiny bulges and may leak slightly, but vision is largely unaffected.
  • Pre-proliferative retinopathy – damage to the blood vessels becomes more pronounced, with significant bleeding into the eye.
  • Proliferative retinopathy – scar tissue and new, fragile blood vessels develop on the retina as the body attempts to maintain the blood supply to the retina. However, these bleed easily, and cause vision loss.

The probability of suffering from diabetic retinopathy is greater if the patient:

  • Has suffered diabetes for many years
  • Has inadequate control of their blood glucose
  • Smokes
  • Suffers from high blood pressure
  • Is obese

Can diabetic retinopathy be prevented?

To avoid diabetic retinopathy, it is essential for diabetic patients to keep their blood glucose, blood pressure and cholesterol under control. Smoking is strongly discouraged.

What is the treatment for diabetic retinopathy?

Patients suffering from the early form of the disease may not require treatment, although it is essential to manage diabetes and monitor the progression of the retinopathy.

For diabetic retinopathy that is affecting vision, the following treatments may be recommended:

  • Laser treatment (photocoagulation) – a laser is used to treat the abnormal blood vessels at the back of the eye in proliferative retinopathy. It usually doesn’t improve vision, but can prevent the condition from worsening.
  • Eye injections
  • Vitrectomy – surgery to remove the vitreous humour (jelly-like substance that fills the eye), performed when there has been significant bleeding into the eye and it is also a useful technique to prevent retinal detachment.
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