Digoxin
What is analysed?
Digoxin is a medication primarily used to treat heart-related conditions. The analysis involves measuring the concentration of digoxin in the blood.
What does the result mean?
The result signifies the level of digoxin in the bloodstream. This information is crucial to ensure the drug is within the therapeutic range, offering maximum benefits with minimal side effects.
Why perform the analysis?
Digoxin has a narrow therapeutic range, meaning the difference between a therapeutic dose and a toxic dose is minimal. Regular analysis helps prevent toxicity and ensures the medication's effectiveness.
When to conduct the analysis?
Digoxin levels should be monitored regularly, especially when initiating treatment, adjusting dosage, or if there are signs of toxicity or inadequate response. Typically, testing occurs 6-8 hours after the last dose.
What sample is required?
A blood sample is required for digoxin analysis. A healthcare professional will draw blood, usually from a vein in the arm.
Is any type of preparation necessary?
It's essential to inform healthcare providers about all medications, including over-the-counter drugs and herbal supplements. Certain medications and conditions can influence Digoxin levels.
How is it used?
Digoxin helps the heart pump more efficiently. It is prescribed for conditions like heart failure and atrial fibrillation. Monitoring ensures the medication's therapeutic benefits while minimising risks.
What are the normal values?
Digoxin Level (ng/mL) |
Interpretation |
Below 0.5 |
Subtherapeutic |
0.5 - 2.0 |
Therapeutic Range |
Above 2.0 |
Potential Toxicity |
What does having altered values mean?
Low Digoxin levels may suggest insufficient therapeutic effects, while high levels can lead to toxicity, causing symptoms like nausea, vomiting, and visual disturbances. Adjustments to the medication dosage may be necessary.