What is being analysed?

Immunoglobulin E (IgE) is a type of antibody produced by the immune system. It plays a crucial role in allergic reactions and in defending the body against parasites. An IgE analysis measures the levels of this antibody in the blood to assess the immune system's response to certain substances.

What is the significance of Immunoglobulin E (IgE) in the immune system

IgE is instrumental in triggering allergic responses. When the immune system encounters allergens, such as pollen or pet dander, it produces IgE antibodies. These antibodies then attach to mast cells and basophils, leading to the release of histamines, and causing allergic symptoms. Understanding IgE levels is vital for diagnosing and managing allergies.

What does the result mean?

Normal IgE levels vary, but elevated levels may indicate an allergic or parasitic condition. Low levels are uncommon but may suggest an impaired immune response. Healthcare providers interpret results in conjunction with clinical symptoms and history for accurate diagnosis and treatment planning.

Why undergo the analysis?

An IgE analysis is recommended for individuals experiencing allergy symptoms, asthma, eczema, or suspected parasitic infections. It helps identify the specific allergens triggering symptoms, guiding appropriate interventions and treatment strategies.

When to undergo the analysis?

Consider an IgE test if you exhibit persistent allergy symptoms like sneezing, itching, or wheezing. It is also indicated if you have unexplained skin conditions or suspected parasitic infections. Your doctor may recommend testing based on your medical history and symptoms.

What sample is required?

IgE testing typically requires a blood sample. A small amount of blood is drawn from a vein, usually in the arm, and sent to the laboratory for analysis. The process is simple and carries minimal discomfort.

Is any preparation required?

Generally, no special preparations like fasting are required for an IgE test. However, inform your healthcare provider about any medications or supplements you are taking, as they may influence the results.

How is it used?

IgE testing is typically conducted using immunoassays, measuring the amount of IgE antibodies in the blood. Results aid healthcare providers in identifying specific allergens, formulating treatment plans, and managing allergic conditions effectively.

What are the normal values?

Normal IgE levels vary by age and individual factors. However, general reference ranges typically fall between 0 and 100 IU/mL. Consult your healthcare provider for specific information relevant to your situation.

What does having altered values mean?

Elevated IgE levels may suggest allergies, asthma, or parasitic infections. Conversely, low levels might indicate an immunodeficiency. These results, when combined with clinical information, guide healthcare providers in accurate diagnosis and personalised treatment plans.

Values table