Prealbumin
What is analysed?
Prealbumin is a protein produced mainly by the liver that helps transport thyroid hormones and vitamin A throughout the body. The prealbumin test measures prealbumin levels in the blood.
What does the result mean?
The result indicates the concentration of prealbumin in the blood. Prealbumin levels serve as a marker of nutritional status, with lower levels typically indicating malnutrition or protein deficiency.
Why conduct the analysis?
The prealbumin test is conducted to help in the assessment of patients with malnutrition, and to monitor response in patients receiving nutritional support.
When to conduct the analysis?
The prealbumin test is conducted when malnourishment is suspected because of a poor diet, eating disorder, or an infection.
What sample is required?
A blood sample is required. The blood is drawn from a vein, usually in the arm.
Is any prior preparation necessary?
No prior preparation is necessary.
How is it performed?
The sample is sent to a specialist laboratory, where it is analysed using immunoassay techniques to detect and quantify the concentration of prealbumin in the sample.
What are the normal values?
Normal values for prealbumin levels may vary among different laboratories. However, typical reference ranges in adults are:
| Interpretation | Prealbumin levels (mg/dL) |
|---|---|
| Normal range for healthy adults | 15 to 35 |
| Low prealbumin levels | Below 15 |
What does having altered values mean?
- High prealbumin levels: High prealbumin levels are less common and may be seen in conditions such as liver disease, chronic inflammation, or certain cancers.
- Low prealbumin levels: Low prealbumin levels are associated with malnutrition, protein deficiency, or conditions causing increased protein turnover, such as severe infections or inflammatory disorders. Patients may benefit from nutritional interventions and close monitoring to prevent complications.